Scientists from Berlin have developed an intravital multiphoton microscopy prototype for repeated retinal measurements in mice. Using this system, Bremer et al. investigated neuronal dysfunction in the retinal ganglion cell layer in an experimental autoimmune uveoretinitis model.
The results of the study have been published in Frontiers in Immunology on Dec 23rd 2016 and are available in full as open access.
Pache & Zimmermann et al. just published a study investigating afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients. MOG-antibodies have recently been identified in a subgroup of patients with neuromyelitis optica and in patients with recurrent optic neuritis.
The paper has been published in Journal of Neuroinflammation 2016 13:282.
The study is part of a series of 4 papers describing different aspects of MOG-IgG in NMO and related disorders.
Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin
Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome
Part 3: Brainstem involvement – frequency, presentation and outcome
Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients
Elena Martinez-Lapiscina and colleagues from Barcelona published a paper on the Usefulness of optical coherence tomography to distinguish optic neuritis associated with AQP4 or MOG in neuromyelitis optica spectrum disorders.
The paper has just been published in Ther Adv Neurol Disord. 2016 Sep; 9(5): 436–440.
It is available online on PubMed Central: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994783/
Figure 1 from Ther Adv Neurol Disord. 2016 Sep; 9(5): 436–440.
It is our pleasure to invite you to our semi-annual IMSVISUAL symposium to discuss updates on vision research in multiple sclerosis. This year at ECTRIMS we are fortunate to have secured Heidelberg engineering as our sponsor. The event will take place on Friday September 16th from 5-8 PM in the Excel Centre. There will be food and beverages.
Space is limited to 48 so we kindly ask that you register using the link below only if you plan to attend.
I think this will be an exciting meeting with presentations from several groups representing existing IMSVISUAL member sites from around the world. There should be ample time for discussion and establishing future collaborations.
We look forward to seeing you there.
Peter Calabresi, Friedemann Paul, Laura Balcer and Pablo Villoslada (board of directors)
Alex Brandt, Rachel Nolan, Elena Hernandez-Martinez and Shiv Saidha (working group committee)